Outeiro, Tiago F : rechercher sur Z-Library

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Articles (160)
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A non-invasive method based on saliva to characterize transthyretin in familial amyloidotic polyneuropathy patients using FT-ICR high-resolution MS

Gonçalo da Costa, Ana Guerreiro, Catarina F. Correia, Ricardo J. Gomes, António Freire, Estela Monteiro, Eduardo Barroso, Ana V. Coelho, Tiago F. Outeiro, Ana Ponces Freire, Carlos Cordeiro

Journal:

PROTEOMICS - Clinical Applications

Année:

2010

Langue:

english

Fichier:

PDF, 153 KB

english, 2010

SIRT1 and SIRT2: emerging targets in neurodegeneration

Donmez, Gizem, Outeiro, Tiago F.

Journal:

EMBO Molecular Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 484 KB

english, 2013

The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease

Marta Amaral, Tiago F. Outeiro, Nigel S. Scrutton…

Journal:

Journal of Molecular Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 342 KB

english, 2013

Glycation in Parkinson's disease and Alzheimer's disease

Vicente Miranda, Hugo, El-Agnaf, Omar M. A., Outeiro, Tiago Fleming

Journal:

Movement Disorders

Année:

2016

Langue:

english

Fichier:

PDF, 512 KB

english, 2016

Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson’s disease

Vicente Miranda, Hugo, Cássio, Rafaela, Correia-Guedes, Leonor, Gomes, Marcos António, Chegão, Ana, Miranda, Elisa, Soares, Tiago, Coelho, Miguel, Rosa, Mário Miguel, Ferreira, Joaquim J., Outeiro, Ti

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 4.12 MB

english, 2017

Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson’s Disease

König, Annekatrin, Vicente Miranda, Hugo, Outeiro, Tiago Fleming

Journal:

Journal of Parkinson s Disease

Année:

2018

Langue:

english

Fichier:

PDF, 260 KB

english, 2018

Zebrafish as an Animal Model for Drug Discovery in Parkinson’s Disease and Other Movement Disorders: A Systematic Review

Vaz, Rita L., Outeiro, Tiago F., Ferreira, Joaquim J.

Journal:

Frontiers in Neurology

Année:

2018

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2018

Prion protein gene polymorphisms in Saccharomyces cerevisiae

Catarina G. Resende, Tiago F. Outeiro, Laina Sands, Susan Lindquist, Mick F. Tuite

Journal:

Molecular Microbiology

Année:

2003

Langue:

english

Fichier:

PDF, 368 KB

english, 2003

The sour side of neurodegenerative disorders: the effects of protein glycation

Hugo Vicente Miranda, Tiago Fleming Outeiro

Journal:

The Journal of Pathology

Année:

2010

Langue:

english

Fichier:

PDF, 313 KB

english, 2010

Assessment of the Efficacy of Solutes from Extremophiles on Protein Aggregation in Cell Models of Huntington’s and Parkinson’s Diseases

Carla D. Jorge, Rita Ventura, Christopher Maycock, Tiago F. Outeiro, Helena Santos, Júlia Costa

Journal:

Neurochemical Research

Année:

2011

Langue:

english

Fichier:

PDF, 304 KB

english, 2011

Increased serum HSP70 levels are associated with the duration of diabetes

Manouchehr Nakhjavani, Afsaneh Morteza, Leila Khajeali, Alireza Esteghamati, Omid Khalilzadeh, Firouzeh Asgarani, Tiago F. Outeiro

Journal:

Cell Stress and Chaperones

Année:

2010

Langue:

english

Fichier:

PDF, 145 KB

english, 2010

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra

Jessie L. St Martin, Jochen Klucken, Tiago F. Outeiro, Paul Nguyen, Christine Keller-McGandy, Ippolita Cantuti-Castelvetri, Tom N. Grammatopoulos, David G. Standaert, Bradley T. Hyman, Pamela J. McL

Journal:

Journal of Neurochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 768 KB

english, 2007

Simple is good: yeast models of neurodegeneration

Sandra Tenreiro, Tiago Fleming Outeiro

Journal:

FEMS Yeast Research

Année:

2010

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2010

Symposium on novel therapeutic opportunities for neurodegenerative disease

Edgar F. da Cruz e Silva, Tiago Fleming Outeiro, Odete A. B. da Cruz e Silva

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 66 KB

english, 2004

Interactions among α-synuclein, dopamine, and biomembranes

Jean-Christophe Rochet, Tiago Fleming Outeiro, Kelly A. Conway, Tomas T. Ding, Michael J. Volles, Hilal A. Lashuel, Robert M. Bieganski, Susan L. Lindquist, Peter T. Lansbury

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 184 KB

english, 2004

Molecular genetics approaches in yeast to study amyloid diseases

Tiago Fleming Outeiro, Paul J. Muchowski

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 370 KB

english, 2004

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Hansen, Christian, Angot, Elodie, Bergström, Ann-Louise, Steiner, Jennifer A., Pieri, Laura, Paul, Gesine, Outeiro, Tiago F., Melki, Ronald, Kallunki, Pekka, Fog, Karina

Journal:

Journal of Clinical Investigation

Année:

2011

Langue:

english

Fichier:

PDF, 6.16 MB

english, 2011

Yeast as a drug discovery platform in Huntington's and Parkinson's diseases

Tiago Fleming Outeiro, Flaviano Giorgini

Journal:

Biotechnology Journal

Année:

2006

Langue:

english

Fichier:

PDF, 557 KB

english, 2006

Yeast as a model for studying human neurodegenerative disorders

Leonor Miller-Fleming, Flaviano Giorgini, Tiago F. Outeiro

Journal:

Biotechnology Journal

Année:

2008

Langue:

english

Fichier:

PDF, 357 KB

english, 2008

Yeast as a model for studying human neurodegenerative disorders

Leonor Miller-Fleming, Flaviano Giorgini, Tiago F. Outeiro

Journal:

Biotechnology Journal

Année:

2008

Langue:

english

Fichier:

PDF, 36 KB

english, 2008

Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease

Michele M. Maxwell, Julien Francisco Zaldivar-Jolissaint, Antonello Mai, Tiago F. Outeiro, Aleksey G. Kazanstev

Journal:

EMBO Molecular Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 93 KB

english, 2012

Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes

Goreti Ribeiro Morais, Hugo Vicente Miranda, Isabel C. Santos, Isabel Santos, Tiago F. Outeiro, Antonio Paulo

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2011

α-Synuclein modifies huntingtin aggregation in living cells

Federico Herrera, Tiago Fleming Outeiro

Journal:

FEBS Letters

Année:

2012

Langue:

english

Fichier:

PDF, 666 KB

english, 2012

Mechanisms of Disease II: Cellular Protein Quality Control

Tiago Fleming Outeiro, Julie Tetzlaff

Journal:

Seminars in Pediatric Neurology

Année:

2007

Langue:

english

Fichier:

PDF, 244 KB

english, 2007

Zooming into protein oligomerization in neurodegeneration using BiFC

Susana A. Gonçalves, Joana E. Matos, Tiago F. Outeiro

Journal:

Trends in Biochemical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 380 KB

english, 2010

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy

Sampaio-Marques, Belém, Felgueiras, Carolina, Silva, Alexandra, Rodrigues, Márcio, Tenreiro, Sandra, Franssens, Vanessa, Reichert, Andreas S., Outeiro, Tiago F., Winderickx, Joris, Ludovico, Paula

Journal:

Autophagy

Année:

2012

Langue:

english

Fichier:

PDF, 2.63 MB

english, 2012

Therapeutic role of sirtuins in neurodegenerative disease

Tiago Fleming Outeiro, Oldriska Marques, Aleksey Kazantsev

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2008

Langue:

english

Fichier:

PDF, 419 KB

english, 2008

Small heat shock proteins protect against α-synuclein-induced toxicity and aggregation

Tiago Fleming Outeiro, Jochen Klucken, Katherine E. Strathearn, Fang Liu, Paul Nguyen, Jean-Christophe Rochet, Bradley T. Hyman, Pamela J. McLean

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2006

Pharmacological inhibition of PARP-1 reduces α-synuclein- and MPP+-induced cytotoxicity in Parkinson’s disease in vitro models

Tiago Fleming Outeiro, Tom N. Grammatopoulos, Steven Altmann, Allison Amore, David G. Standaert, Bradley T. Hyman, Aleksey G. Kazantsev

Journal:

Biochemical and Biophysical Research Communications

Année:

2007

Langue:

english

Fichier:

PDF, 441 KB

english, 2007

Angiotensin II protects against α-synuclein toxicity and reduces protein aggregation in vitro

Tom N. Grammatopoulos, Tiago F. Outeiro, Bradley T. Hyman, David G. Standaert

Journal:

Biochemical and Biophysical Research Communications

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

Brit Mollenhauer, Valerie Cullen, Ilana Kahn, Bryan Krastins, Tiago F. Outeiro, Imelda Pepivani, Juliana Ng, Walter Schulz-Schaeffer, Hans A. Kretzschmar, Pamela J. McLean, Claudia Trenkwalder, David

Journal:

Experimental Neurology

Année:

2008

Langue:

english

Fichier:

PDF, 976 KB

english, 2008

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice

Susanna Kemppainen, Tomi Rantamäki, André Jerónimo-Santos, Gregoire Lavasseur, Henri Autio, Nina Karpova, Elisa Kärkkäinen, Saara Stavén, Hugo Vicente Miranda, Tiago F. Outeiro, Maria J. Diógenes, Ser

Journal:

Neurobiology of Aging

Année:

2012

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2012

Epigenetics in neurodegeneration: A new layer of complexity

Sueli C.F. Marques, Catarina R. Oliveira, Claudia M.F. Pereira, Tiago F. Outeiro

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Année:

2011

Langue:

english

Fichier:

PDF, 430 KB

english, 2011

Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast

Swinnen, Erwin, Büttner, Sabrina, Outeiro, Tiago F., Galas, Marie‑Christine, Madeo, Frank, Winderickx, Joris, Franssens, Vanessa

Journal:

Biochemical Society Transactions

Année:

2011

Langue:

english

Fichier:

PDF, 417 KB

english, 2011

Impairment of the septal cholinergic neurons in MPTP-treated A30P α-synuclein mice

Éva M. Szegő, Tiago F. Outeiro, Pawel Kermer, Jörg B. Schulz

Journal:

Neurobiology of Aging

Année:

2013

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2013

The zebrafish homologue of Parkinson's disease ATP13A2 is essential for embryonic survival

Lopes da Fonseca, Tomás, Correia, Ana, Hasselaar, Wiebren, van der Linde, Herma C., Willemsen, Rob, Outeiro, Tiago Fleming

Journal:

Brain Research Bulletin

Année:

2013

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2013

Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice

Éva M. Szegő, Ellen Gerhardt, Tiago F. Outeiro, Pawel Kermer

Journal:

Journal of the Neurological Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 813 KB

english, 2011

Assessing the Subcellular Dynamics of Alpha-synuclein Using Photoactivation Microscopy

Gonçalves, Susana, Outeiro, Tiago Fleming

Journal:

Molecular Neurobiology

Année:

2013

Langue:

english

Fichier:

PDF, 787 KB

english, 2013

LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell models

Guerreiro, PatrÃcia Silva, Huang, Yue, Gysbers, Amanda, Cheng, Danni, Gai, Wei Ping, Outeiro, Tiago Fleming, Halliday, Glenda Margaret

Journal:

Journal of Molecular Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 527 KB

english, 2013

Structural basis of kynurenine 3-monooxygenase inhibition

Amaral, Marta, Levy, Colin, Heyes, Derren J., Lafite, Pierre, Outeiro, Tiago F., Giorgini, Flaviano, Leys, David, Scrutton, Nigel S.

Journal:

Nature

Année:

2013

Langue:

english

Fichier:

PDF, 937 KB

english, 2013

Heat-mediated enrichment of α-synuclein from cells and tissue for assessing post-translational modifications

Miranda, Hugo Vicente, Xiang, Wei, de Oliveira, Rita M., Simões, Tânia, Pimentel, José, Klucken, Jochen, Penque, Deborah, Outeiro, Tiago F.

Journal:

Journal of Neurochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 716 KB

english, 2013

alpha-Synuclein and intracellular trafficking: impact on the spreading of Parkinson’s disease pathology

Eisbach, Sibylle E., Outeiro, Tiago F.

Journal:

Journal of Molecular Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 564 KB

english, 2013

Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson's disease

Faria, Cristiana, Jorge, Carla D., Borges, Nuno, Tenreiro, Sandra, Outeiro, Tiago F., Santos, Helena

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

2013

Langue:

english

Fichier:

PDF, 647 KB

english, 2013

Harnessing the power of yeast to unravel the molecular basis of neurodegeneration

Tenreiro, Sandra, Munder, Matthias C., Alberti, Simon, Outeiro, Tiago F.

Journal:

Journal of Neurochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 496 KB

english, 2013

Live-cell imaging of p53 interactions using a novel Venus-based bimolecular fluorescence complementation system

Amaral, Joana Dias, Herrera, Federico, Rodrigues, Pedro Miguel, Dionísio, Pedro Antunes, Outeiro, Tiago Fleming, Rodrigues, Cecília Maria Pereira

Journal:

Biochemical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2013

The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation

Pais, Teresa Faria, Szegő, Éva M, Marques, Oldriska, Miller-Fleming, Leonor, Antas, Pedro, Guerreiro, Patrícia, de Oliveira, Rita Machado, Kasapoglu, Burcu, Outeiro, Tiago Fleming

Journal:

The EMBO Journal

Année:

2013

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2013

Visualization of cell-to-cell transmission of mutant huntingtin oligomers

Herrera, Federico, Tenreiro, Sandra, Miller-Fleming, Leonor, Outeiro, Tiago Fleming

Journal:

PLoS Currents

Année:

2011

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2011

Challenges and Promises in the Development of Neurotrophic Factor-Based Therapies for Parkinson’s Disease

Rodrigues, Tiago Martins, Jerónimo-Santos, André, Outeiro, Tiago Fleming, Sebastião, Ana Maria, Diógenes, Maria José

Journal:

Drugs & Aging

Année:

2014

Langue:

english

Fichier:

PDF, 544 KB

english, 2014

β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons

Taschenberger, Grit, Toloe, Johan, Tereshchenko, Julia, Akerboom, Jasper, Wales, Pauline, Benz, Roland, Becker, Stefan, Outeiro, Tiago F., Looger, Loren L., Bähr, Mathias, Zweckstetter, Markus, Kügler

Journal:

Annals of Neurology

Année:

2013

Langue:

english

Fichier:

PDF, 495 KB

english, 2013

Amyloidogenesis: FlAsH illuminates Aβ aggregation

Outeiro, Tiago F

Journal:

Nature Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 678 KB

english, 2011